KHSRP Has Oncogenic Functions and Regulates the Expression and Alternative Splicing of DNA Repair Genes in Breast Cancer MDA-MB-231 Cells

Researchers silenced KH-type splicing regulatory protein (KHSRP) expression in MDA-MB-231 cells by small interfering RNA (siKHSRP), and then assessed its effects on cellular features. In siKHSRP samples, the proliferation, invasion, and migration abilities were significantly repressed compared with negative control samples.