Bile Acid Metabolites Enhance Expression of Cathelicidin Antimicrobial Peptide in Airway Epithelium through Activation of the TGR5-ERK1/2 Pathway

Researchers investigated the effects of bile acid metabolites produced from lithocholic acid by microbiota, on the regulation of innate immune responses connected to the expression of host defense peptide cathelicidin in lung epithelial cells.