MiR-204 Suppresses Cancer Stemness and Enhances Osimertinib Sensitivity in Non-Small Cell Lung Cancer by Targeting CD44

Scientists explored novel miRNA–mRNA regulatory mechanisms that contribute to osimertinib resistance in lung cancer. They found that miR-204 expression in osimertinib-resistant lung cancer cells was markedly reduced compared to that in osimertinib-sensitive parental cells.