Proanthocyanidins Inhibited Colorectal Cancer Stem Cell Characteristics Through Wnt/β-Catenin Signaling

CCK-8, colony, and tumorsphere formation assay were used to evaluate cancer cell viability and stemness, respectively. Western blotting was used to detect the protein expression. Tumor xenograft experiments were employed to examine the tumorigenicity of colorectal cancer cells in nude mice.