Sequentially Degradable Hydrogel-Microsphere Loaded with Doxorubicin and Pioglitazone Synergistically Inhibits Cancer Stemness of Osteosarcoma

Researchers reported a treatment strategy for osteosarcoma using hydrogel−microspheres complex mainly composed of collagenase and PLGA microspheres carrying Pioglitazone and Doxorubicin.