YAP/BRD4-Controlled ROR1 Promotes Tumor-Initiating Cells and Hyperproliferation in Pancreatic Cancer

Scientists showed that a cellular subpopulation with partial epithelial-mesenchymal transition-like signature marked by high expression of receptor tyrosine kinase-like orphan receptor 1 (ROR1) was the origin of heterogeneous tumor cells in pancreatic ductal adenocarcinoma.