ER-Localized JmjC Domain-Containing Protein JMJD8 Targets STING to Promote Immune Evasion and Tumor Growth in Breast Cancer

Researchers demonstrated that an endoplasmic reticulum (ER)-localized JmjC domain-containing protein, JMJD8, inhibited STING-induced type I interferon responses to promote immune evasion and breast tumorigenesis.