SERPINA12 Promotes the Tumorigenic Capacity of Hepatocellular Carcinoma Stem Cells through Hyperactivation of AKT/ β-Catenin Signaling

Transcriptome profiling of epithelial-specific ‘normal’ CD133+ cells isolated from fetal and regenerating liver against ‘HCC’ CD133+ cells isolated from proto-oncogene driven and inflammation-associated HCC revealed preferential overexpression of SERPINA12 in HCC but not fetal and regenerating liver CD133+ cells.