Irisin and ALCAT1 Mediated Aerobic Exercise-Alleviated Oxidative Stress and Apoptosis in Skeletal Muscle of Mice with Myocardial Infarction

Fndc5^−/− and Alcat1^−/− mice were used to establish the myocardial infarction (MI) model. C2C12 cells were treated with H₂O₂ and recombinant human Irisin, or transduced with a lentiviral vector to mediate overexpression of ALCAT1.