Single-Cell Dissection of Remodeled Inflammatory Ecosystem in Primary and Metastatic Gallbladder Carcinoma

Investigators validated significant overexpression of PLA2G2A across in situ gallbladder carcinoma (GBC) cells, together with increased proliferation and cancer stemness in PLA2G2A-overexpressing GBC cells, indicating an important role for PLA2G2A during early carcinogenesis.