 | Vol. 3.29 – 28 July, 2022 |
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| Scientists described a system, called BEHAV3D, developed to study the dynamic interactions of immune cells and patient cancer organoids by means of imaging and transcriptomics. [Nature Biotechnology] |
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PUBLICATIONSRanked by the impact factor of the journal |
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| Transcriptomics and proteomics approaches identified molecular pathways significantly upregulated in geographic atrophy, including in mitochondrial functions, metabolic pathways and extracellular cellular matrix reorganization. [Nature Communications] |
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| Detergents, like sodium dodecyl sulfate, are common ingredients in household products like dish soap and toothpaste. Scientists hypothesized detergent exposure decreases epithelial barrier function and induces esophageal inflammation. [Allergy] |
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| The authors examined the potential of mouse epiblast stem cells cultured in media containing Wnt pathway inhibitors as a starting point for directed differentiation. [Development] |
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| Scientists developed a setup combining tissue expansion and light sheet fluorescence microscopy for imaging and quantifying diverse spatial parameters during organoid development. [Development] |
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| Rat bone marrow-mesenchymal stem cells were treated with homogenates of decellularized rat salivary gland-extracellular matrix for one hour in cell suspension and then cultured in tissue culture plates for seven days in growth media. [Stem Cell Research & Therapy] |
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| The authors developed a method for generating murine kidney organoids with improved higher-order structure, through stages using chimaeras of ex-fetu and PSC-derived cells to a system that works entirely from ESCs. [Scientific Reports] |
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| Brain organoids were characterized regarding brain development, cell type composition, and Machado-Joseph disease-associated neuropathology markers, to evaluate their value for cerebellar diseases modeling. [Scientific Reports] |
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| Scientists assessed estrogen regulation of endometrial function by integrating the estrogen receptor alpha cistromes and transcriptomes of endometrial biopsies taken from the proliferative and mid-secretory phases of the menstrual cycle together with hormonally stimulated endometrial epithelial organoids. [Endocrinology] |
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| Human mini brains are micro-scale physiological systems consisting of mixed populations of neural progenitor cells, glial cells, and neurons that may represent key features of human brain anatomy and function. [Journal of Tissue Engineering] |
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| Two of Yale’s stem cell faculty — Drs. Haifan Lin, and Valentina Greco— are serving in the highest ranks of the International Society for Stem Cell Research. [Yale School of Medicine] |
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| September 11 – 13, 2022 Lisbon, Portugal |
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| Warsaw University of Technology – Warsaw, Poland |
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| The University of British Columbia – Vancouver, British Columbia, Canada |
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| Ohio State University Wexner Medical Center – Columbus, Ohio, United States |
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| Weill Cornell Medical College – New York, New York, United States |
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| Lehigh University – Bethlehem, Pennsylvania, Untied States |
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