 | | Vol. 12.09 – 8 March, 2023 |
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| Researchers described single-cell proteogenomics analyses, transcriptome-wide analyses of FACS-purified hematopoietic stem and progenitor cells followed by differential splicing analyses, dual-fluorescence lentiviral splicing reporter assays, and Rebecsinib in pediatric acute myeloid leukemia.
[Cell Reports Medicine] |
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 | | PUBLICATIONSRanked by the impact factor of the journal |
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| Scientists established a syngeneic orthotopic transplantation model in mice based on intestinal cancer organoids to profile quiescent CSCs.
[Cancer Research] |
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| Researchers observed that nicotinamide phosphoribosyltransferase reduction caused a decrease in tumorigenic and stemness properties, migration capacity, and CSC phenotype through nicotinamide adenine dinucleotide (NAD) pool depletion.
[Journal of Experimental & Clinical Cancer Research] |
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| Investigators found that plasmacytoma variant translocation 1 (PVT1) was highly expressed in endometrial cancers and endometrial CSCs (ECSCs), correlated with poor patient prognosis, promoted the malignant behavior and the stemness of endometrial cancer cells and ECSCs.
[Cell Death & Disease] |
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| Researchers posited that pluripotent, endogenous, tissue-resident, very small embryonic-like stem cells that exist in small numbers in all adult tissues, exit from their quiescent state due to epigenetic changes in response to various insults and transform into CSCs to initiate cancer.
[Stem Cells] |
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| The authors analyzed the key regulatory cell death genes involved in heat stress and esophageal carcinoma (ESCA) progression by using The Cancer Genome Atlas-ESCA database.
[International Immunopharmacology] |
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| HY1-Pt showed highly efficient anti-tumor effect with low toxicity for either cisplatin-sensitive or cisplatin-resistant epithelial ovarian cancer both in vitro and in vivo.
[The International Journal of Biochemistry & Cell Biology] |
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| Scientists reported a new methodology, which optimized the culture conditions for CTCs using primary cancer cells as a model system.
[Scientific Reports] |
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| The authors developed an EpCAM-independent circulating tumor cells (CTC) isolation method that isolated a broader range of living CTC from small-cell lung cancer and deciphered their genomic and biological characteristics.
[Scientific Reports] |
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| Investigators discuss the function of carbohydrates as prospective serum biomarkers, some clinically authorized biomarkers, and potential novel biomarkers relating to cancer disease diagnosis and prognosis.
[Glycobiology] |
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| The authors review the roles of breast CSCs in the occurrence, development, and management of breast cancer treatment resistance.
[International Journal of Oncology] |
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| The total cost of cancer to the global economy will reach 25.2 trillion international dollars between 2020 and 2050, according to an analysis of 29 cancers across 204 countries.
[Nature] |
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| April 24 – 26, 2023
Hinxton, England, United Kingdom |
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| | University of British Columbia – Vancouver, British Columbia, Canada |
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| | Beth Israel Deaconess Medical Center – Boston, Massachusetts, United States |
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| | Rutgers Biomedical and Health Sciences – New Brunswick, New Jersey, United States |
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| | Weill Cornell College of Medicine – New York, New York, United States |
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| | Albert Einstein College of Medicine – New York, New York, United States |
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Cancer Stem Cell News
Cell Therapy News
Dermal Cell News
Endothelial Cell News
ESC & iPSC News
Extracellular Matrix News
Hematopoiesis News
Hepatic Cell News
Human Immunology News
Immune Regulation News
Intestinal Cell News
Mammary Cell News
Mesenchymal Cell News
Muscle Cell News
Neural Cell News
Organoid News
Pancreatic Cell News
Prostate Cell News
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