Muscle Cell News

Muscle Cell News is an online resource dedicated to the latest research into smooth, skeletal, and cardiac muscle cells.

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Precision BioSciences Receives FDA Fast Track Designation for PBGENE-DMD and Announces Duchenne Muscular Dystrophy Investor Event

March 23, 2026

[Precision BioSciences, Inc. (Business Wire)] Precision BioSciences, Inc., announced that the US FDA has granted Fast Track designation to PBGENE-DMD for the treatment of Duchenne muscular dystrophy (DMD)

YAP Induces a Prorenewal Metabolic State in Cardiomyocytes

March 23, 2026

[Circulation] Researchers investigated the role of YAP in mediating metabolic remodeling to overcome the cardiomyocyte proliferation barrier and enable cardiac regenerative repair after heart injury.

Restoration of RBM22 Overcomes the Transcriptional and Epigenetic Barriers of Cardiomyocyte Proliferation for Heart Regeneration

March 23, 2026

[Nature Communications] Scientists identified RNA-binding motif 22 (RBM22) as a pivotal regulator of cardiomyocyte proliferation. Cardiomyocyte-specific deletion of Rbm22 impaired neonatal heart regeneration and exacerbated post-infarction ventricular remodeling in adult mice.

Smarce1-Dependent Modulation of Stat3 Signaling Governs Cardiomyocyte Proliferation

March 23, 2026

[Biological Research] Investigators identified Smarce1, a core subunit of the SWI/SNF chromatin-remodeling complex, as a key regulator of cardiomyocyte proliferation in zebrafish.

LncRNA MEG3 Regulates the Development of Porcine Skeletal Muscle Satellite Cells by Enhancing HMGA1 Stability

March 23, 2026

[Cellular & Molecular Biology Letters] The authors aimed to explore the mechanism whereby long noncoding RNA MEG3 (LncRNA MEG3) modulates porcine skeletal muscle satellite cell development.

Aerobic Exercise Stabilizes Atherosclerotic Plaques by Suppressing miR-15a-5p-Mediated Repression of Semaphorin-3A in Vascular Smooth Muscle Cells

March 23, 2026

[Life Sciences] Researchers investigated whether aerobic exercise stabilizes atherosclerotic plaques by reprogramming vascular smooth muscle cell microRNA expression, focusing on the miR-15a-5p/Semaphorin-3A axis.

Betulinic Acid Attenuates Vascular Smooth Muscle Cell Senescence and Aortic Vascular Aging via PPAR-α/CPT1A-Mediated Fatty Acid Oxidation

March 23, 2026

[Rejuvenation Research] Scientists aimed to determine whether betulinic acid mitigates cellular senescence by inhibiting the peroxisome proliferator-activated receptor alpha (PPAR-α)/carnitine palmitoyl transferase 1A (CPT1A) signaling pathway, modulating fatty acid oxidation, and reducing reactive oxygen species production.

Ferroptosis of Smooth Muscle Cells in Vascular Diseases: From Basic Principles to Clinical Translation

March 23, 2026

[Cell Death Discovery] Investigators summarize the current evidence, underlying potential mechanisms, and therapeutic targets of vascular smooth muscle cell ferroptosis in vascular diseases.

SLC4A3-Related Short QT Syndrome Assessed in Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes: Mechanisms of Ventricular Arrhythmia and Sudden Cardiac Death

March 9, 2026

[European Heart Journal] Human induced pluripotent stem cell-derived cardiomyocytes from each index short QT syndrome patient were developed, as well as an isogenic cell line with variant correction and HEK 293T cells transfected with SLC4A3 expression constructs expressing either wild type SLC4A3 or the variants.

Highly Integrated Chip for Continuous Chemical Synthesis, Purification, and Inline Biosensoric Monitoring of Biological Activity on Stem Cell-Derived 3D Cardiomyocyte Cultures

March 9, 2026

[Biosensors & Bioelectronics] The synthesis of the cardioactive drug propranolol from its precursor was chosen and successfully established in a continuous microfluidic setup. For sensitive detection of bioactivity, human stem cell-derived cardiomyocyte 3D cultures were used.

PFKM Governs Metabolic Shifts Throughout Skeletal Muscle Differentiation

March 9, 2026

[Nature Metabolism] Researchers revealed spatiotemporal dynamics of phosphofructokinase 1, a key glycolytic enzyme, within the skeletal muscle lineage.

Bioengineered Human Pre-Vascularized Microtissues Reconstruct Vascular Niche and Regenerative Microenvironment to Enhance Functional Skeletal Muscle Regeneration

March 9, 2026

[Biomaterials] Scientists highlighted that human pre-vascularized microtissue can effectively re-establish the vascular regenerative microenvironment, which presented an innovative therapeutic approach to promote functional skeletal muscle regeneration following volumetric muscle loss.

Every day, our editorial team sifts through the most recent scientific literature to help keep researchers and medical professionals current. Muscle Cell News covers the three types of muscle cells: cardiac, skeletal, and smooth muscle. We cover a broad range of topics, including cell culturing, muscle regeneration, and musculoskeletal disorders.