Cancer Stem Cell News
Cell Therapy News
Dermal Cell News
Endothelial Cell News
ESC & iPSC News
Extracellular Matrix News
Hematopoiesis News
Hepatic Cell News
Human Immunology News
Immune Regulation News
Intestinal Cell News
Mammary Cell News
Mesenchymal Cell News
Muscle Cell News
Neural Cell News
Organoid News
Pancreatic Cell News
Prostate Cell News
Pulmonary Cell News
Cancer Stem Cell News
Cancer Stem Cell News is an online resource that curates the top research publications and reviews about cancer progenitor cells and cancer stem cells.
GPLD1+ Cancer Stem Cells Contribute to Chemotherapy Resistance and Tumor Relapse in Intestinal Cancer
[Journal of Biochemistry] Scientists suggested that targeting of glycosylphosphatidylinositol-specific phospholipase D1 (GPLD1) in colorectal cancer might contribute to a new therapeutic strategy that was based on suppression of Wnt signaling and epithelial-mesenchymal transition-related cancer progression driven by cancer stem cells.
The IL-10/STAT3 Axis Nasopharyngeal Carcinoma Cancer Stem Cell and Radio Resistance
[Scientific Reports] Investigators found that IL-10 was up-regulated in CSC. IL-10 enhanced the self-renewal and tumorigenesis of nasopharyngeal CSC.
A Magnetic-Responsive Biomimetic Nanosystem Coated with Glioma Stem Cell Membranes Effectively Targets and Eliminates Malignant Gliomas
[Biomaterials Research] This study positioned FDPM, a magnetic-responsive biomimetic nanosystem, as a promising nanoplatform to target glioma stem cells and related tumor cells for improving the therapeutic effect of glioma.
Calpain 2 Promotes Lenvatinib Resistance and Cancer Stem Cell Traits via Both Proteolysis-Dependent and Independent Approach in Hepatocellular Carcinoma
[Molecular Biomedicine] Researchers employed integrated bioinformatic analysis to identify calpain-2 as a novel key regulator for Lenvatinib resistance in HCC, and its expression greatly increased in both Lenvatinib-resistant HCC cell lines and clinical samples.
MACC1 Ablation Suppresses the Dedifferentiation Process of Non-CSCs in Lung Cancer Through Stabilizing KLF4
[Cell Death Discovery] The authors showed that metastasis-associated in colon cancer-1 (MACC1) promoted the transition from non-cancer stem cell (CSC) to CSC in lung cancer.
CALML3-AS1 Enhances Malignancies and Stemness of Small Cell Lung Cancer Cells through Interacting with DAXX Protein and Promoting GLUT4-Mediated Aerobic Glycolysis
CALML3 antisense RNA 1 (CALML3-AS1), an oncogene, promoted the malignancy and stemness of small cell lung cancer (SCLC) cells by interacting with death domain-associated...
Stabilization of SQLE mRNA by WTAP/FTO/IGF2BP3-Dependent Manner in HGSOC: Implications for Metabolism, Stemness, and Progression
[Cell Death & Disease] Squalene epoxidase overexpression resulted in enhanced cancer stem cell-like properties, including increased tumorsphere formation and stemness markers expression.
Aging Limits Stemness and Tumorigenesis by Reprogramming Iron Homeostasis
[Nature] Investigators used physiologically aged autochthonous genetically engineered mouse models and primary cells to demonstrate that ageing suppresses lung cancer initiation and progression by degrading the stemness of the alveolar cell of origin.
Cannabidiol Effects in Stem Cells: A Systematic Review
[Biofactors] In this systematic review, the authors analyzed the effect of cannabidiol on both somatic stem cells and cancer stem cells.
SUO-CTC and CG Oncology Announce the First Annual Non-Muscle Invasive Bladder Cancer (NMIBC) Research Fellowship Award
[CG Oncology, Inc.] The Society of Urologic Oncology Clinical Trials Consortium (SUO-CTC), and CG Oncology, Inc. announced the first annual CG-SUO-CTC NMIBC Research Fellowship designed to support the development of outstanding clinical cancer research investigators who have demonstrated a commitment to improving the understanding and treatment of NMIBC.
Dysregulation of the p53 Pathway Provides a Therapeutic Target in Aggressive Pediatric Sarcomas with Stem-Like Traits
[Cellular Oncology] Investigators showed that restoring canonical p53 activity provided a promising strategy for developing improved therapies for pediatric sarcomas with unfavorable stem-like traits.
YAP1 Induces Bladder Cancer Progression and Promotes Immune Evasion Through IL-6/ STAT3 Pathway and CXCL Deregulation
[Journal of Clinical Investigation] Investigators provided insights on YAP1 signaling as a driver for cancer stemness and an inducer of immunosuppressive tumor immune microenvironment.
Cancer Stem Cell News consolidates the most recent publications covering research areas such as the identification and isolation of cancer stem cells, their proliferation and differentiation characteristics, gene expression and regulatory pathways, and the development of anti-cancer therapies. We also include cancer stem cell jobs and events hosted by leading research organizations, societies, and institutes.
