Noshin Noorjahan

[Haematologica] Scientists retrospectively studied 97 AML patients with trisomy 19 treated between 2001 and 2019 within two multicenter study groups. Tris-19 occurred solely in 10, with additional abnormalities in non-complex karyotypes in 8 and within complex karyotypes in 79 patients.

[Annals of Hematology] The authors describe the hematologic differences among neonatal subgroups and the major underlying pathogenic mechanisms. Issues that should be taken into account when interpreting neonatal hematological parameters are also highlighted.

[AstraZeneca] AstraZeneca’s tablet formulation of Calquence has been approved in the European Union (EU) for the treatment of adult patients with chronic lymphocytic leukemia.

[Cardiovascular Research] Researchers recreated elevated endothelium shear stress in vitro to identify potential pathological mechanisms that might be of relevance to plaque erosions in acute coronary syndromes.

[Journal of Experimental & Clinical Cancer Research] To determine the functions and underlying mechanisms of tumor cell-derived exosomes in angiogenesis and tip cell formation, exosomes derived from serum of colorectal cancer (CRC) patients with metastasis/non-metastasis and CRC cells were isolated by ultracentrifugation.

[Angiogenesis] Investigators used a tissue-engineered post-capillary venule model incorporating stem cell derived induced brain microvascular endothelial-like cells and pericyte-like cells to visualize the dynamics of angiogenesis.