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Noshin Noorjahan
Endothelial Cell News
Filamin a Pre-mRNA Editing Modulates Vascularization and Tumor Growth
[Molecular Therapy-Nucleic Acids] Using transgenic mice expressing either constitutively edited or constitutively uneditable Filamin A, scientists showed that Filamin A editing critically controled angiogenesis in tumors as well as in a mouse ischemia model.
Endothelial Cell News
Biomarkers of Alveolar Epithelial Injury and Endothelial Dysfunction Are Associated with Scores of Pulmonary Edema in Invasively Ventilated Patients
[American Journal of Physiology-Lung Cellular and Molecular Physiology] Plasma levels of surfactant protein-D, soluble receptor for advanced glycation end products, and angiopoietin-2 (Ang-2) were measured in a prospective, multicenter cohort of invasively ventilated patients.
Endothelial Cell News
Intraprocedural Endothelial Cell Seeding of Arterial Stents via Biotin/Avidin Targeting Mitigates In-Stent Restenosis
[Scientific Reports] Investigators reported on the novel stent endothelialization strategy of post-deployment seeding of biotin-modified endothelial cells to avidin-functionalized stents.
Endothelial Cell News
Paricalcitol Protects against Hydrogen Peroxide-Induced Injury in Endothelial Cells through Suppression of Apoptosis
[Experimental Biology and Medicine] Scientists investigated the restorative and protective potentials of paricalcitol, a vitamin D analogue, which was frequently used in patients with chronic renal failure in human umbilical vein endothelial cells before and after H2O2-induced oxidative stress.
Endothelial Cell News
Diabetic Retinopathy and Corneal Endothelial Parameters: An Analytical Cross-Sectional Study
[BMC Ophthalmology] In this descriptive-analytical cross-sectional study, corneal endothelium parameters including endothelial cell density, average cell size, coefficient of variation in cell size, and hexagonality were evaluated by non-contact specular microscopy.
Endothelial Cell News
Role of Anti-Vascular Endothelial Growth Factor in the Management of Non-Proliferative Diabetic Retinopathy without Center-Involving Diabetic Macular Edema: A Meta-Analysis of Trials
[Eye] The authors reviewed the impact of anti-vascular endothelial growth factor treatment in management of eyes with non-proliferative diabetic retinopathy without center involving diabetic macular edema.
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Survival Outcomes of Apalutamide as a Starting Treatment: Impact in Real-World Patients With Metastatic Hormone Sensitive Prostate Cancer (OASIS)
[Prostate Cancer and Prostatic Diseases] Scientists evaluated the impact of upfront therapy for metastatic hormone-sensitive prostate cancer on outcomes in real-world clinical practice in the United States.
A TBX2-Driven Signaling Switch From Androgen Receptor to Glucocorticoid Receptor Confers Therapeutic Resistance in Prostate Cancer
[Oncogene] Using human prostate cancer and CRPC cell line models, scientists demonstrated that TBX2 downregulated androgen receptor and upregulated glucocorticoid receptor through direct transcriptional regulation.
Radiotherapy-Resistant Prostate Cancer Cells Escape Immune Checkpoint Blockade through the Senescence-Related Ataxia Telangiectasia and Rad3-Related Protein
[Cancer Communications] Scientists identified a subset of prostate cancer cells that exhibited resistance to radiotherapy, characterized by a reduced antigen presentation capability, which enhanced their ability to evade immune detection and resist cytotoxic T-lymphocyte-associated protein 4 (CTLA-4) blockade.
