Noshin Noorjahan

Endothelial Cell News

PRMT1 Ablation in Endothelial Cells Causes Endothelial Dysfunction and Aggravates COPD Attributable to Dysregulated NF-κB Signaling

[Advanced Science] The role of protein arginine methyltransferase 1 (PRMT1) was investigated in endothelial cells, particularly in the context of chronic obstructive pulmonary disease (COPD) pathogenesis.

Endothelial Cell News

SOAT1 Activates NLRP3 Inflammasome to Promote Cancer-Related Lymphangiogenesis and Metastasis via IL-1β/IL-1R-1 Axis in Oral Squamous Cell Carcinoma

[Molecular Carcinogenesis] Investigators found that SOAT1 was overexpressed in oral squamous cell carcinoma (OSCC) and promoted proliferation, migration, and invasion of OSCC cells.

Newsletters

The Expression Order Determines the Pioneer Functions of NGN3 and NEUROD1 in Pancreatic Endocrine Differentiation

[Science Advances] Researchers investigated how the sequential expression of neurogenin 3 (NGN3) and NEUROD1 affects their pioneering functions during pancreatic endocrine differentiation.

Newsletters

GLP-1 Receptor Agonists Causing Euglycemic Ketoacidosis in Patients without Diabetes: A Brief Review

[International Journal of Obesity] The authors discuss the known literature on euglycemic ketoacidosis associated with GLP-1RA and the risk factors for the condition.

Newsletters

Lactylation Increases the Stability of RBM15 to Drive M6a Modification in Non-Small-Cell Lung Cancer Cells

[FASEB Journal] Scientists observed that L-lactate upregulated RNA-binding protein 15 (RBM15) protein levels in non-small-cell lung cancer cell lines A549 and H23 in a time- and dosage-dependent manner.

Newsletters

UK Medicines and Healthcare Products Regulatory Agency Confirms Acceptance of Marketing Authorization Application for Proposed Biosimilar to Xolair® (omalizumab)

[Advanz Pharma] Alvotech, Kashiv Biosciences LLC, and ADVANZ PHARMA, announced that the UK Medicines and Healthcare Products Regulatory Agency has accepted a marketing application for AVT23, a proposed biosimilar to Xolair®.

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Inosine from Purine Metabolism Enhances Fracture Healing by Coupling Fibrinolysis and Angiogenesis of Type H Vessels

[Biochimica Et Biophysica Acta-General Subjects] The metabolic control of fibrinolysis-type H angiogenesis coupling in fracture healing remains unclear. HUVECs and MC3T3-E1 cells were employed as in vitro models to examine the effects of identified metabolites on endothelial events and osteogenesis.

Alcon Acquires Majority Interest in Aurion Biotech, Inc. to Advance Innovative Cell Therapy for Corneal Endothelial Disease

[Alcon] Alcon announced it had acquired a majority interest in Aurion Biotech, Inc., a clinical-stage company developing advanced cell therapies to treat eye diseases.

Flow Sensitive Ion Channels in Vascular Endothelial Cells: Mechanisms of Activation and Roles in Mechanotransduction

[Biochemical and Biophysical Research Communications] The authors evaluated the current knowledge about the mechanisms by which mechanosensitive ion channels are activated by fluid shear stress in endothelial cells.

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Noshin Noorjahan

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