lbeveridge

[Heliyon] Investigators utilized quantitative proteomics to investigate the mechanism of TGF-β-induced fibrosis-like changes in mouse epithelial cells. Their findings revealed that TGF-β significantly impacted biological processes related to the endoplasmic reticulum, mitochondrion, and ribonucleoprotein complex.

[Scientific Reports] Patients with early-stage NSCLC with a tumor size ≤ 2.0 cm were chosen from the SEER database. The influence of confounding factors was minimized by 1:1 propensity score matching.

[Cell Death & Disease] Investigators found that IRE1α signaling, one of the canonical UPR arms, is increased in prostate cancer patient tumors.

[Scientific Reports] A reduced graphene oxide-cobalt nickel tungsten boron oxide nanocomposite was synthesized by the chemical reduction method via a one-pot reduction method followed by calcination at 500°C under a nitrogen environment for two hours and characterized by UV-Vis, XRD, TGA, and SEM.

[Med] Researchers conducted an exploratory analysis of the CHART trial which investigated prostate-specific antigen (PSA) kinetics and the correlation between PSA and survival outcomes in high-volume, metastatic, hormone-sensitive prostate cancer.

[Urologic Oncology-Seminars and Original Investigations] The authors examine the molecular mechanisms associated with LGR5 and emphasizes methodologies aimed at targeting LGR5 to enhance understanding and promote the development of LGR5-specific therapies.