Justin.choi

Endothelial Cell News

Adverum Biotechnologies Doses First Patient in Cohort 4 of OPTIC Phase I Clinical Trial of ADVM-022 Intravitreal Gene Therapy for Wet AMD

[Adverum Biotechnologies, Inc.] Adverum Biotechnologies, Inc. announced that the first patient was dosed in Cohort 4 of the ongoing OPTIC Phase I clinical trial for ADVM-022 for the treatment of wet age-related macular degeneration (AMD).

Open Science Takes On the Coronavirus Pandemic

[Nature Technology Feature] When reports emerged in late 2019 of an outbreak of a new coronavirus centred in Wuhan, China, researchers at the virological-analysis website Nextstrain were ready. The open-source project tracks the spread of viruses through genetic variations in the sequences that scientists find.

Director of US Agency Key to Vaccine Development Leaves Role Suddenly Amid Coronavirus Pandemic

[STAT News] Rick Bright, one of the nation’s leading vaccine development experts and the director of the Biomedical Advanced Research and Development Authority, is no longer leading the organization.

CIRP Contributes to Multiple Organ Damage in Acute Pancreatitis by Increasing Endothelial Permeability

[Communications Biology] Acute pancreatitis was induced by two hourly intraperitoneal injections of 4.0 g/kg l-arginine in wild-type or cold-inducible RNA-binding protein (CIRP) knockout mice.

CircSARS-CV2-N1368 from SARS-CoV-2 Impairs Endothelial Cell Function through the Upregulation of ATF7 to Activate TLR4/NF-κB/ROS Signaling

[Acta Pharmacologica Sinica] Three circRNAs derived from the nucleocapsid gene of SARS-CoV-2, namely, circSARS-CV2-Ns, were identified for functional studies.

Compensatory Lymphangiogenesis Is Required for Edema Resolution in Zebrafish

[Scientific Reports] Researchers subjected zebrafish larvae to osmotic stress using hypertonic and isotonic solutions to induce osmotic imbalance and subsequent edema formation.

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