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Pulmonary Cell NewsAll Articles by Author:
Justin.choi
Cancer Stem Cell News
SH3RF3 Promotes Breast Cancer Stem-Like Properties via JNK Activation and PTX3 Upregulation
[Nature Communications] Scientists identified a scaffold protein SH3RF3 that was upregulated in CSCs of breast cancer clinical tumors and cancer cell lines, and enhanced the CSC properties of breast cancer cells.
Cancer Stem Cell News
Critical Role of SOX2–IGF2 Signaling in Aggressiveness of Bladder Cancer
[Scientific Reports] Researchers found SOX2 expression signifies poor recurrence-free survival and correlates with advanced pathological grade in bladder cancer. SOX2 silencing attenuated bladder cancer cell growth, while its expression promoted cancer cell survival and proliferation.
Cancer Stem Cell News
Disrupting Mitochondrial Copper Distribution Inhibits Leukemic Stem Cell Self-Renewal
[Cell Stem Cell] The authors found increased mRNA expression of mitochondrial intermembrane assembly pathway substrates in acute myeloid leukemia stem cells.
Cancer Stem Cell News
Integrin-Linked Kinase Mediates Therapeutic Resistance of Quiescent CML Stem Cells to Tyrosine Kinase Inhibitors
[Cell Stem Cell] Researchers showed integrin-linked kinase, a key constituent of focal adhesions, is highly expressed in TKI-nonresponsive patient cells and their LSCs.
Cancer Stem Cell News
Different Shades of L1CAM in the Pathophysiology of Cancer Stem Cells
[Journal of Clinical Medicine] The authors summarize the role of L1CAM in cancer focusing on its functional contribution to CSC pathophysiology.
Cancer Stem Cell News
NCCN Foundation Awards Leading Young Investigators Advancing Cancer Research for Adults and Children
[National Comprehensive Cancer Network] The National Comprehensive Cancer Network® and the NCCN Foundation® announced five new recipients for the 10th annual NCCN Foundation Young Investigator Awards Program.
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ACSS1-Dependent Acetate Utilization Rewires Mitochondrial Metabolism to Support AML and Melanoma Tumor Growth and Metastasis
[Cell Reports] Scientists reported that acetyl-CoA synthetases (ACSS) 1 and 2 were differentially expressed in cancer. ACSS1 knockdown decreased acute myeloid leukemia burden in vivo and inhibited melanoma tumor and metastatic growth.
Sanofi, A*STAR, and the National Skin Centre Partner to Advance Research in Acne Treatment
[A*STAR] Sanofi, the Agency for Science, Technology and Research (A*STAR), and the National Skin Centre Singapore established a Memorandum of Understanding to advance research in acne treatment. This collaboration will encompass a Phase I clinical study in patients with mild acne.
RTI Surgical Announces First Patient Enrolled in Investigational Device Exemption (IDE) for Cortiva® Allograft Dermis in Breast Reconstruction
[RTI Surgical] RTI Surgical announced the enrollment of the first patient in ADMIRE. This IDE study is designed to confirm the safety and effectiveness of Cortiva® Allograft Dermis in implant-based breast reconstruction.
