All Articles by Author:

Jamie Kang

The Underappreciated Role of Resident Epithelial Cell Populations in Metastatic Progression: Contributions of the Lung Alveolar Epithelium

[American Journal of Physiology-Cell Physiology] This review examines the potential contributions of the alveolar epithelium to metastatic progression.

C-Mpl-Del, a C-mpl Alternative Splicing Isoform, Promotes AMKL Progression and Chemoresistance

[Small] To develop in vitro models than can retain cellular features of glioma cells, a 3D-engineered scaffold, fabricated by two-photon polymerization, was developed as a cell culture model system to study patient-derived glioma cells.

EMulate Therapeutics Announces the Publication of Positive Pre-clinical Data Evaluating Pain Reduction via Delivery of Low and Ultra-low Radio Frequency Energy

[EMulate Therapeutics (Globe Newswire)] EMulate Therapeutics announced the publication of positive preclinical data evaluating the use of its light-weight wearable device that uses proprietary WAV files to deliver specific low to ultra-low radio frequency energy (ulRFE®) to reduce visceral, neuropathic, and inflammatory pain.

LEXEO Therapeutics Receives Orphan Drug Designation for LX1004 from European Commission

[LEXEO Therapeutics] LEXEO Therapeutics announced that the European Commission has granted Orphan Drug Designation to LX1004 for the treatment of CLN2 Batten disease.

3D-Engineered Scaffolds to Study Microtubes and Localization of Epidermal Growth Factor Receptor in Patient-Derived Glioma Cells

[Small] To develop in vitro models than can retain cellular features of glioma cells, a 3D-engineered scaffold, fabricated by two-photon polymerization, was developed as a cell culture model system to study patient-derived glioma cells.

USP36 Promotes Tumorigenesis and Drug Sensitivity of Glioblastoma by Deubiquitinating and Stabilizing ALKBH5

[Neuro-Oncology] Investigators elucidated the signaling pathways involved in mediating ALKBH5 protein stability in facilitating the development of glioblastomas.

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Creative Medical Technology Holdings Expands Collaboration with Greenstone Biosciences to Accelerate iPSCelz Pipeline Development

[Creative Medical Technology Holdings, Inc. (BioSpace)] Creative Medical Technology Holdings, Inc. announced an expanded agreement with Greenstone Biosciences, Inc. to leverage atificial intelligence in further developing its human iPSC platform for diabetes treatment.

Streamlined Regulatory Documentation Accelerates Development of Next Generation Therapies

[Pluristyx] Pluristyx submitted a Type II Drug Master File (DMF) to the US FDA for its PluriBankâ„¢ CG (Clinical Grade) iPSC lines.

Atlas of Multilineage Stem Cell Differentiation Reveals TMEM88 as a Developmental Regulator of Blood Pressure

[Nature Communications] Scientists engineered barcoded iPSCs to generate an atlas of multilineage differentiation from pluripotency, encompassing an eight-day time course with modulation of WNT, BMP, and VEGF signaling pathways.