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Jamie Kang
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Biodesix Awarded U.S. Federal Supply Schedule Contract for Its Comprehensive Lung Cancer Diagnostic Testing Solutions
[Biodesix, Inc.] Biodesix, Inc. announced the award of a U.S. Federal Supply Schedule contract which included the Veterans Health Administration providing care for U.S. Veterans and the Military Health System providing care for active-duty service members and their families.
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Aptar Digital Health Announces Strategic Partnership with the Chiesi Group
[Aptar Digital Health] Aptar Digital Health, part of Aptar Pharma, announced a strategic partnership with the Chiesi Group, the international research-focused biopharmaceutical and healthcare group, to bring to market a disease management platform for asthma and COPD.
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Particulate Matter Exposure Exacerbates Cellular Damage by Increasing Stress Granule Formation in Respiratory Syncytial Virus-Infected Human Lung Organoids
[Environmental Pollution] Investigators studied the effects of atmospheric and diesel particulate matter on respiratory syncytial virus infection in human two-dimensional lung epithelial cells and human three-dimensional lung organoids mimicking the lung tissue.
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Nedd4L Suppression in Lung Fibroblasts Facilitates Pathogenesis of Lung Fibrosis
[Translational Research] Scientists found that NEDD4 Like E3 Ubiquitin Protein Ligase (Nedd4L) levels were significantly suppressed in lung myofibroblasts in idiopathic pulmonary fibrosis patients, experimental pulmonary fibrosis, and TGF-β1-treated lung fibroblasts.
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Microvascular Lung Injury and Endoplasmic Reticulum Stress in SLE-Associated Alveolar Hemorrhage and Pulmonary Vasculitis
[American Journal of Physiology-Lung Cellular and Molecular Physiology] Researchers studied the effects of systemic lupus erythematosus and COPA syndrome on diffuse alveolar hemorrhage (DAH) and endoplasmic reticulum (ER) stress. They found pristane-induced DAH may be initiated by endothelial injury, resulting in ER stress, apoptosis of lung endothelial cells, and recruitment of myeloid cells that propagate lung injury.
Mesenchymal Cell News
Mesenchymal Stem Cell Bioenergetics and Apoptosis Are Associated with Risk for Bronchopulmonary Dysplasia in Extremely Low Birth Weight Infants
[Scientific Reports] Investigators tested whether differences in endogenous mesenchymal stem cell mitochondrial bioenergetics, proliferation, and survival were associated with bronchopulmonary dysplasia risk in extremely low birth weight infants.
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Creative Medical Technology Holdings Expands Collaboration with Greenstone Biosciences to Accelerate iPSCelz Pipeline Development
[Creative Medical Technology Holdings, Inc. (BioSpace)] Creative Medical Technology Holdings, Inc. announced an expanded agreement with Greenstone Biosciences, Inc. to leverage atificial intelligence in further developing its human iPSC platform for diabetes treatment.
Streamlined Regulatory Documentation Accelerates Development of Next Generation Therapies
[Pluristyx] Pluristyx submitted a Type II Drug Master File (DMF) to the US FDA for its PluriBankâ„¢ CG (Clinical Grade) iPSC lines.
Atlas of Multilineage Stem Cell Differentiation Reveals TMEM88 as a Developmental Regulator of Blood Pressure
[Nature Communications] Scientists engineered barcoded iPSCs to generate an atlas of multilineage differentiation from pluripotency, encompassing an eight-day time course with modulation of WNT, BMP, and VEGF signaling pathways.