Jamie Kang

Immune Regulation News

Gut Microbiota Contributes to the Intestinal and Extraintestinal Immune Homeostasis by Balancing Th17/Treg Cells

[International Immunopharmacology] The authors provided an overview of gut microbiota, along with Th17/Treg cell differentiation and cytokine production.

Immune Regulation News

Quell Therapeutics Achieves Milestone for Type 1 Diabetes CAR-Treg Cell Therapy Program

[Quell Therapeutics, Ltd.] Quell Therapeutics, Ltd. announced that AstraZeneca has selected a candidate to progress in the Type 1 Diabetes Treg cell therapy program.

Immunology of Infectious Disease News

Avian TRIM13 Attenuates Antiviral Innate Immunity by Targeting MAVS for Autophagic Degradation

[Autophagy] Scientists identified the duck Anas platyrhynchos domesticus TRIM13 as a novel negative regulator of duck MAVS that mediated the antiviral innate immune response.

Immunology of Infectious Disease News

The Intestinal Microbiome and Cetobacterium somerae Inhibit Viral Infection through TLR2-Type I IFN Signaling Axis in Zebrafish

[Microbiome] Researchers used a rhabdoviral infection model in zebrafish, which allowed them to investigate the modes of action of microbiome-mediated antiviral effect.

Immunology of Infectious Disease News

Rapid Biphasic Decay of Intact and Defective HIV DNA Reservoir during Acute Treated HIV Disease

[Nature Communications] Leveraging >500 longitudinal samples from 67 people living with HIV treated during acute infection, researchers developed a mathematical model to predict reservoir decay from peripheral CD4+ T cells.

Immunology of Infectious Disease News

Mycobacterium tuberculosis Antigen Rv1471 Induces Innate Immune Memory and Adaptive Immunity against Infection

[Journal of Infectious Diseases] Scientists tested Rv1471, a thioredoxin secreted by mycobacterium tuberculosis, as a candidate tuberculosis vaccine antigen due to its capacity to stimulate mouse bone marrow-derived macrophages.

123...844 Page 2 of 844

A PSMA-Targeted Tri-Specific Killer Engager Enhances NK Cell Cytotoxicity Against Prostate Cancer

[Cancer Immunology Research] Scientists reported that the prostate-specific membrane antigen (PSMA) Tri-specific Killer Engager specifically bound to PSMA-expressing cells and significantly enhanced expansion, degranulation, and cytokine production of NK cells derived from healthy donors or prostate cancer patients.

Osteoblast-Derived ECM1 Promotes Anti-Androgen Resistance in Bone Metastatic Prostate Cancer

[Advanced Science] Researchers demonstrated that under enzalutamide treatment, osteoblasts in the bone microenvironment secrete increased levels of extracellular matrix protein 1 (ECM1), which affected surrounding prostate cancer cells, promoting tumor cell proliferation and anti-androgen resistance.

Rapid Modulation of Striatal Cholinergic Interneurons and Dopamine Release by Satellite Astrocytes

[Nature Communications] Scientists discovered that striatal astrocytes occupied a cell type-specific anatomical and functional relationship with cholinergic interneurons (ChIs), through which they rapidly excited ChIs and governed dopamine release via nicotinic acetylcholine receptors on subsecond timescales.

All Articles by Author:

Jamie Kang

Popular