Jamie Kang

[Journal of Physiology] Researchers suggested that combined exercise training elicited beneficial muscular adaptations without impairing important indicators of skeletal muscle regenerative capacity in patients with facioscapulohumeral muscular dystrophy (FSHD).

[European Heart Journal] CCN5 exerted a dual protective effect on in-stent restenosis (ISR) by inhibiting vascular smooth muscle cell proliferation and facilitating endothelial cell repair. CCN5rp-coated stent might be promising in the prevention of ISR after percutaneous coronary intervention.

[Cell Communication and Signaling] The authors discuss recent advances on the role of protease-activated receptors signalling on vascular smooth muscle cells and specifically their role in vascular remodelling contributing to cardiovascular disease.

[Tenaya Therapeutics, Inc.] Tenaya Therapeutics, Inc. announced that the California Institute for Regenerative Medicine (CIRM), a state of California Agency that funds regenerative medicine, stem cell, and gene therapy research, has awarded Tenaya Therapeutics an $8.0 million CLIN2 grant.

[Gut] The authors provided accurate advanced neoplasia (AN) risk stratification in ulcerative colitis patients with low-grade dysplasia (LGD). They hypothesized that the pattern and burden of somatic genomic copy number alterations (CNAs) in LGD lesions could predict future AN risk.

[Journal of Crohn's & Colitis] Given the crucial function of such receptors in intestinal epithelial cells, researchers assessed the involvement of protein tyrosine phosphatase non-receptor type 23 (PTPN23) in intestinal homeostasis and epithelial proliferation.