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Pulmonary Cell NewsAll Articles by Author:
Britya Ghosh
Cancer Stem Cell News
Disruption of β-Catenin-Mediated Negative Feedback Reinforces cAMP-Induced Neuronal Differentiation in Glioma Stem Cells
[Cell Death & Disease] Scientists demonstrated that cAMP triggered neuronal differentiation and compromised the self-renewal capacity in glioma stem cells.
Cancer Stem Cell News
GSK3β Palmitoylation Mediated by ZDHHC4 Promotes Tumorigenicity of Glioblastoma Stem Cells in Temozolomide-Resistant Glioblastoma through the EZH2–STAT3 Axis
[Oncogenesis] Researchers found that GSK3β was noted as a substrate for ZDHHC4-mediated palmitoylation at the Cys14 residue, which enhanced glioblastoma temozolomide resistance and glioblastoma stem cell self-renewal.
Cancer Stem Cell News
ΔNp63α Mediates Sulforaphane Suppressed Colorectal Cancer Stem Cell Properties through Transcriptional Regulation of Nanog/Oct4/Sox2
[Journal of Nutritional Biochemistry] Scientists showed that ΔNp63α expression was enhanced in sphere-forming colorectal cancer cells.
Cancer Stem Cell News
Identification of Two Cancer Stem Cell-Like Populations in Triple-Negative Breast Cancer Xenografts
[Disease Models & Mechanisms] The multiple-microtissue transcriptome analysis revealed three cancer cell-type clusters in the primary tumor and axillary lymph node metastasis, two of which were CSC-like clusters.
Cancer Stem Cell News
GM-CSF-miRNA-Jak2/Stat3 Signaling Mediates Chemotherapy-Induced Cancer Cell Stemness in Gastric Cancer
[Frontiers in Pharmacology] Researchers treated two human gastric cancer cell lines SGC7901 and BGC823 with 5-Fluorouracil or Cisplatin in vitro.
Cancer Stem Cell News
Recombinant Expression a Novel Fibronectin—Collage Fusion Peptide Modulating Stem Cell Stemness via Integrin β3
[Applied Microbiology and Biotechnology] A novel recombinant protein fibronectin-collagen peptide was designed to modulate the function of extracellular matrix expressed by Picha. pastoris strain X33.
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Fucoxanthin Suppresses Pancreatic Cancer Progression by Inducing Bioenergetics Metabolism Crisis and Promoting SLC31A1‑Mediated Sensitivity to DDP
[International Journal of Oncology] MTT and colony formation assay were performed to detect cell growth and viability in pancreatic cancer cells. Levels of ROS in whole cell and mitochondria were analyzed through flow cytometry.
GABA and GLP-1 Receptor Agonist Combination Therapy Modifies Diabetes and Langerhans Islet Cytoarchitecture in a Rat Model of Wolfram Syndrome
[Diabetology & Metabolic Syndrome] Five-month-old glucose intolerant Wolfram syndrome rats and their wild-type littermates were daily treated with GABA, liraglutide, or a combination of both.
Pancreatic Alpha and Beta Cell Fate Choice Is Directed by Apical-Basal Polarity Dynamics
[Developmental Cell] The authors identified apical-basal polarity as the main regulator of the differentiation of multipotent pancreatic Neurogenin3+ endocrine progenitors into the beta or alpha cell fates.
