Cardiac Fibroblast BAG3 Regulates TGFBR2 Signaling and Fibrosis in Dilated Cardiomyopathy

Scientists used an isogenic pair of Bcl2-associated athanogene 3 (BAG3)-knockout and wild-type human iPSCs (hiPSCs) to interrogate the role of BAG3 in hiPSC-derived cardiac fibroblasts.