Recombinant Newcastle Disease Virus Harboring PTEN Suppresses Pancreatic Ductal Adenocarcinoma Growth by Inhibiting PI3K/AKT/mTOR Signaling and Promoting Apoptosis

Researchers created a recombinant Newcastle disease virus containing the PTEN gene to investigate its PDAC cell-killing and tumor-suppression effects in PDAC cells transplanted into mice.