Multi-Omics Analysis Unveils the Predictive Value of IGF2BP3/SPHK1 Signaling in Cancer Stem Cells for Prognosis and Immunotherapeutic Response in Muscle-Invasive Bladder Cancer

The authors performed single-cell mass cytometry analysis of 179,483 single cells to characterize potential immunotherapy-related CSCs-like populations in the tumor microenvironment of 38 muscle invasive bladder cancer tissues.