Bone Tissue Engineering Using 3D Silk Scaffolds and Human Dental Pulp Stromal Cells Epigenetic Reprogrammed with the Selective Histone Deacetylase Inhibitor MI192

Investigators investigated the potential of using a selective HDAC2 and 3 inhibitor, MI192, to promote human dental pulp stromal cells bone-like tissue formation in vitro and in vivo within porous Bombyx Mori silk scaffolds.