Silencing of circDPP4 Suppresses Cell Progression of Human Prostate Cancer and Enhances Docetaxel Cytotoxicity through Regulating miR-564/ZIC2 Axis

Expression of circular RNA derived from dipeptidyl peptidase 4 (circDPP4) was upregulated in prostate cancer (PC) tumors from 60 patients and PC cell lines, and higher circDPP4 might predict poor overall survival. Decreasing circDPP4 suppresses cell proliferation, colony formation, migration/invasion, and 50% inhibitory concentration of docetaxel in PC cells.