Disrupting Mitochondrial Copper Distribution Inhibits Leukemic Stem Cell Self-Renewal

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The authors found increased mRNA expression of mitochondrial intermembrane assembly pathway substrates in acute myeloid leukemia stem cells.
[Cell Stem Cell]
Ostrander, E. L., Kramer, A. C., Mallaney, C., Celik, H., Koh, W. K., Fairchild, J., Haussler, E., Zhang, C. R. C., & Challen, G. A. (2020). Divergent Effects of Dnmt3a and Tet2 Mutations on Hematopoietic Progenitor Cell Fitness. Stem Cell Reports, 0(0). https://doi.org/10.1016/j.stemcr.2020.02.011 Cite
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