[Inflammation and Regeneration] Researchers developed an ex vivo murine lung-organoid model designed to induce and activate aberrant basaloid cells. The organoids were subjected to bleomycin stimulation.

[Cell Stem Cell] The authors generated human nucleus basalis of Meynert organoids from hPSCs containing functional cholinergic projection neurons.

[Cellular and Molecular Life Sciences] Through quantitative proteomic analysis of Parechovirus ahumpari 3 (HPeV-3) infected neural organoids, investigators identified unique metabolic changes following HPeV-3 infection that indicate immunometabolic dysregulation.

[Advanced Materials] Researchers presented the Centrifugal Mechanical Testing platform, which enables rapid, robust, and label-free mechanotyping of 3D organoids.

[Cell Stem Cell] Researchers presented a California Institute of Regenerative Medicine-initiated neurodevelopmental disorder biobank of 352 publicly available genetically diverse patient-derived iPSCs, along with clinical details, brain imaging, and genomic data.

[Nature Biomedical Engineering] Scientists developed a bioinspired, non-expansive biodegradable matrix through covalent–non-covalent assembly of commercially available, clinical-grade natural polymers.

[Cell Reports Medicine] The authors uncovered a biphasic mechanism of ATG-induced microvasculopathy using a humanized liver organoid platform derived from iPSCs.

[Stem Cell Reports] Investigators produced human gastric organoids from hESCs engineered with inducible expression of reprogramming factors.

[Stem Cell Research & Therapy] The authors summarize the molecular regulatory mechanisms underlying sweat gland development and focus on the latest progress in sweat gland organoid construction.

[Journal of Translational Medicine] Investigators focus on stem cell-based neuronal repair by using biomaterials. They discuss neural tissue damage and the associated mechanisms in neuronal repair.

[The Scientist] In the past decade, human neural organoid research has been moving at a “break-neck pace,” but it lacks the legal and ethical guidelines that should accompany a field that is “peculiarly ethically sensitive.”

[Cell Communication and Signaling] Scientists explored the role of chemokine signaling pathways in melanoma immunotherapy.