CD86

[Proceedings of the National Academy of Sciences of the United States of America] Investigators demonstrated that teprotumumab, an anti-insulin-like growth factor I receptor inhibitor, attenuated constitutive expression and induction by the thyroid-stimulating hormone of MHC II and these B7 members in CD34+ fibrocytes.

[Hypertension Research] Using multicolor flow cytometry, expression of maturation markers in total dendritic cells (DCs), myeloid DCs, and plasmacytoid DCs and the distribution of peripheral Th17-bearing and T-reg cells were defined.

[Blood] Investigators showed that concurrent ASXL1 and NRAS mutations defined a population of chronic myelomonocytic leukemia patients with shorter leukemia-free survival than those with ASXL1 mutation only.

[Proceedings of the National Academy of Sciences of the United States of America] Investigators showed that Treg-expressed CTLA-4 facilitated Treg-antigen-presenting cells conjugation and immune synapse formation.

[Cellular & Molecular Immunology] Researchers described that in addition to the DC deficiency, several DC activation and homing markers were altered in acute COVID-19 patients, which were associated with multiple inflammatory markers.

[Cancer Immunology Research] Researchers used multicolor flow cytometry and immunohistochemistry to elucidate abundance and spatial distribution of these antigen-presenting B cells in blood and tumor samples of 238 cancer patients.