In cell lines derived from Parkinson’s disease patients, astrocytes were characterized by a significant decrease in S100B and GFAP-positive astrocytic profiles associated with marked decrease in astrocyte complexity.
[npj Parkinsons Disease]
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Ramos-Gonzalez, P., Mato, S., Chara, J. C., Verkhratsky, A., Matute, C., & Cavaliere, F. (2021). Astrocytic atrophy as a pathological feature of Parkinson’s disease with LRRK2 mutation. Npj Parkinson’s Disease, 7(1), 1–11. https://doi.org/10.1038/s41531-021-00175-w Cite
