FAO-fueled OXPHOS and NRF2-mediated stress resilience in MICs drive lymph node metastasis

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Researchers highlighted the pivotal roles of fatty acid oxidation-fueled oxidative phosphorylation (OXPHOS) and NRF2 in LN metastasis and suggested targeting these pathways as a promising therapeutic strategy for metastatic esophageal squamous cell carcinoma.
[Proceedings of The National Academy of Sciences of The United States of America]
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