Peptide-Oligonucleotide Nanohybrids Designed for Precise Gene Therapy of Rheumatoid Arthritis

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A novel kind of engineered peptide and oligonucleotide nanohybrids were designed and fabricated, which provide various advantages including good biosafety, inflammatory region-targeted delivery, cell membrane penetration, reactive oxygen species scavenging, and endolysosomal escape.
[Advanced Materials]
Abstract