Focusing on four FLI1 variants, two of which were novel, investigators assessed the impact of FLI1 variants on megakaryopoiesis using single-cell RNA sequencing. Defects were confirmed in patient platelets and cell lines.
[Haematologica]
Home Newsletters Hematopoiesis News FLI1 and GATA1 Govern TLN1 Transcription: New Insights into FLI1-Related Platelet Disorders
