Conditional loss of Beclin 1 (Becn1) caused sequential dysfunction and exhaustion of fetal liver hematopoietic stem cells, leading to lethal inflammatory cell-biased hematopoiesis in the fetus.
[Journal of Clinical Investigation]
Beclin 1 Prevents ISG15-Mediated Cytokine Storms to Secure Fetal Hematopoiesis and Survival
