Researchers elucidated that DNA damage activated Chk2, leading to the phosphorylation of serine 164 on C-terminal binding protein 2 (Ctbp2).
[Nucleic Acids Research]
Phosphorylation-Mediated Disassembly of C-Terminal Binding Protein 2 Tetramer Impedes Epigenetic Silencing of Pluripotency in Mouse Embryonic Stem Cells
