PGC-1α Drives Small Cell Neuroendocrine Cancer Progression Toward an ASCL1-Expressing Subtype with Increased Mitochondrial Capacity

By
Emily Salmini
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Analyses using a human prostate tissue-based small cell neuroendocrine transformation system showed that the achaete-scute homolog 1 (ASCL1) subtype heightened PGC-1α expression and oxidative phosphorylation activity.
[Proceedings of The National Academy of Sciences of The United States of America]
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