Clinical Outcomes of Autologous Adipose-Derived Mesenchymal Stem Cell Combined with High Tibial Osteotomy for Knee Osteoarthritis Are Correlated with Stem Cell Stemness and Senescence

In this prospective randomized trial, 45 knee osteoarthritis patients were divided into two groups: group 1 patients treated with high tibial osteotomy (HTO) alone and group 2 patients treated with HTO followed by intra-articular injection of autologous adipose-derived-MSCs.