Schistosoma Heamatobium Tetraspanins TSP-2 and TSP-6 Induce Dendritic Cells Maturation, Cytokine Production and T Helper Cells Differentiation In Vitro

The authors investigated the role of Sh-TSP-2, Sh-TSP-6 and Sh-TSP-23, which were expressed in the parasite’s tegument and extracellular vesicles. Immature dendritic cells from unexposed healthy donors were stimulated with these proteins to evaluate maturation maker expression and cytokine production.