PIWIL2/PDK1 Axis Promotes the Progression of Cervical Epithelial Lesions via Metabolic Reprogramming to Maintain Tumor-Initiating Cell Stemness

Researchers revealed that aberrant pyruvate dehydrogenase kinase 1 (PDK1) expression was closely related to aerobic glycolysis in squamous intraepithelial lesions and poor survival in patients with cervical cancer.