Lymphocyte Antigen 6 Family Member E Suppresses Apoptosis and Promotes Pancreatic Cancer Growth and Migration via Wnt/β-Catenin Pathway Activation

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Investigators reported that lymphocyte antigen 6 family member (LY6E) knockdown inhibited proliferation, invasion, and migration of pancreatic cancer cells, while enhancing apoptosis evidenced by increased cleaved caspase 3 levels and alterations in the Bcl-2/Bax ratio.
[Scientific Reports]
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