NewslettersMammary Cell News Phase Separation of Phospho-HDAC6 Drives Aberrant Chromatin Architecture in Triple-Negative Breast Cancer By Noshin Noorjahan - August 28, 2024 0 111 Scientists demonstrated that phosphorylated histone deacetylase 6 (phospho-HDAC6) formed liquid–liquid phase separation condensates in the nuclei of TNBC cells that were essential for establishing aberrant chromatin architecture. [Nature Cancer] Abstract