Mechanical Stimulation-Induced Purinome Priming Fosters Osteogenic Differentiation and Osteointegration of Mesenchymal Stem Cells from the Bone Marrow of Post-menopausal Women

Bone marrow-derived MSCs were harvested from the neck of femora of Pm women undergoing total hip replacement. The cells grew, for 35 days, in an osteogenic-inducing medium either submitted or not to MS twice a week.