NewslettersPancreatic Cell News IDH1 Inhibition Potentiates Chemotherapy Efficacy in Pancreatic Cancer By Emily Salmini - June 10, 2024 0 Pharmacologic inhibition of wild-type IDH1 with ivosidenib synergized with conventional chemotherapeutics in vitro and potentiated the efficacy of sub-therapeutic doses of these drugs in vivo in murine PDAC models. [Cancer Research] Abstract