The authors generated heterozygous HNF1B mutant kidney organoids from CRISPR-Cas9 gene-edited human ESCs and induced PSCs reprogrammed from a family with HNF1B-associated dysplastic kidney malformations.
[Stem Cell Reports]
Home Newsletters Human Pluripotent Stem Cell-Derived Kidney Organoids Reveal Tubular Epithelial Pathobiology of Heterozygous...
