The authors found that DNA methyltransferase 1 (DNMT1) deficiency led to cell cycle arrest of erythroid progenitors which was partially rescued by treatment with a p21 inhibitor UC2288.
[Cell Death & Differentiation]
DNMT1 Regulates Human Erythropoiesis by Modulating Cell Cycle and Endoplasmic Reticulum Stress in a Stage-Specific Manner
