BHLHE40 Inhibits Ferroptosis in Pancreatic Cancer Cells via Upregulating SREBF1

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Researchers highlighted the important roles of basic helix-loop-helix transcription factor 40 (BHLHE40)-mediated lipid peroxidation in inducing ferroptosis in pancreatic cancer (PCa) cells and provided a novel mechanism underlying sterol regulatory element-binding factor 1 (SREBF1) overexpression in PCa.
[Advanced Science]
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