CD44+ Lung Cancer Stem Cell-Derived Pericyte-Like Cells Cause Brain Metastases through GPR124-Enhanced Trans-Endothelial Migration

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Researchers reported that vascular pericytes derived from CD44+ lung CSCs in lung adenocarcinoma potently caused brain metastases through the G-protein-coupled receptor 124 (GPR124)-enhanced trans-endothelial migration.
[Cancer Cell]
AbstractGraphical Abstract